3-phenacyl-UDP [Ligand Id: 1745] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL215294 (phenacyl-UDP)
  • P2Y2 receptor/Purinergic receptor P2Y2 in Human [ChEMBL: CHEMBL4398] [GtoPdb: 324] [UniProtKB: P41231]
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  • P2Y4 receptor/Pyrimidinergic receptor P2Y4 in Human [ChEMBL: CHEMBL2123] [GtoPdb: 325] [UniProtKB: P51582]
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  • P2Y6 receptor/Pyrimidinergic receptor P2Y6 in Human [ChEMBL: CHEMBL4714] [GtoPdb: 326] [UniProtKB: Q15077]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
P2Y2 receptor/Purinergic receptor P2Y2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4398] [GtoPdb: 324] [UniProtKB: P41231]
ChEMBL Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as IP accumulation by SPA F 6 pEC50 >1000 nM EC50 J. Med. Chem. (2006) 49: 7076-7087 [PMID:17125260]
P2Y4 receptor/Pyrimidinergic receptor P2Y4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2123] [GtoPdb: 325] [UniProtKB: P51582]
ChEMBL Agonist activity at human P2Y4 receptor expressed in 1321N1 cells assessed as IP accumulation by SPA F 4 pEC50 >100000 nM EC50 J. Med. Chem. (2006) 49: 7076-7087 [PMID:17125260]
P2Y6 receptor/Pyrimidinergic receptor P2Y6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4714] [GtoPdb: 326] [UniProtKB: Q15077]
ChEMBL Agonist activity at human P2Y6 receptor expressed in 1321N1 cells assessed as IP accumulation by SPA F 7.15 pEC50 70 nM EC50 J. Med. Chem. (2006) 49: 7076-7087 [PMID:17125260]
ChEMBL Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay F 7.15 pEC50 70 nM EC50 J. Med. Chem. (2010) 53: 4488-4501 [PMID:20446735]
GtoPdb - - 7.2 pEC50 - - - J Med Chem (2006) 49: 7076-87 [PMID:17125260]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]