nomifensine   Click here for help

GtoPdb Ligand ID: 4792

Synonyms: Alival® | Merital®
Approved drug
nomifensine is an approved drug (FDA (approval date not specified, withdrawn 1992))
Compound class: Synthetic organic
Comment: Nomifensine is a norepinephrine-dopamine reuptake inhibitor. Bioactivity is reported to lie with the (S) isomer.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 29.26
Molecular weight 238.15
XLogP 2.29
No. Lipinski's rules broken 0
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Canonical SMILES CN1CC(c2ccccc2)c2c(C1)c(N)ccc2
Isomeric SMILES CN1CC(c2ccccc2)c2c(C1)c(N)ccc2
InChI InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (approval date not specified, withdrawn 1992))
Withdrawn drug? Yes
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
2920 nomifensine
Synonyms Click here for help
Alival® | Merital®
Database Links Click here for help
CAS Registry No. 24526-64-5 (source: Scifinder)
ChEMBL Ligand CHEMBL273575
DrugBank Ligand DB04821
DrugCentral Ligand 1958
GtoPdb PubChem SID 178101494
PubChem CID 4528
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UniChem Compound Search for chemical match using the InChIKey XXPANQJNYNUNES-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey XXPANQJNYNUNES-UHFFFAOYSA-N
Wikipedia Nomifensine