lesogaberan   Click here for help

GtoPdb Ligand ID: 7705

Synonyms: AZD-3355 | AZD3355
Compound class: Synthetic organic
Comment: Lesogaberan is an agonist of gamma-aminobutyric acid receptor B (GABAB). This was an investigational compound tested for potential to treat gastroesophageal reflux disease (GERD). This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 86.79
Molecular weight 141.04
XLogP -1.12
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES NCC(CP(=O)O)F
Isomeric SMILES NC[C@H](CP(=O)O)F
InChI InChI=1S/C3H9FNO2P/c4-3(1-5)2-8(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m1/s1
InChI Key LJNUIEQATDYXJH-GSVOUGTGSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
[(2R)-3-amino-2-fluoropropyl]phosphinic acid
International Nonproprietary Names Click here for help
INN number INN
9048 lesogaberan
Synonyms Click here for help
AZD-3355 | AZD3355
Database Links Click here for help
CAS Registry No. 344413-67-8
ChEMBL Ligand CHEMBL448343
GtoPdb PubChem SID 223366038
PubChem CID 16686147
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Wikipedia Lesogaberan