desflurane   Click here for help

GtoPdb Ligand ID: 7156

Synonyms: I-653 | Suprane®
Approved drug
desflurane is an approved drug (FDA (1992))
Compound class: Synthetic organic
Comment: Desflurane is a highly fluorinated methyl ethyl ether general anaesthetic. it is a racemic mixture of (R) and (S) optical isomers (enantiomers). We show the chemical structure without specified stereochemistry to represent the mixture. Desflurane is a greenhouse gas.
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: desflurane

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 9.23
Molecular weight 168
XLogP 2.47
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES FC(OC(C(F)(F)F)F)F
Isomeric SMILES FC(OC(C(F)(F)F)F)F
InChI InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6505 desflurane
Synonyms Click here for help
I-653 | Suprane®
Database Links Click here for help
CAS Registry No. 57041-67-5
ChEMBL Ligand CHEMBL1200733
DrugBank Ligand DB01189
DrugCentral Ligand 811
GtoPdb PubChem SID 178103731
PubChem CID 42113
Search Google for chemical match using the InChIKey DPYMFVXJLLWWEU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DPYMFVXJLLWWEU
Search PubMed clinical trials desflurane
Search PubMed titles desflurane
Search PubMed titles/abstracts desflurane
UniChem Compound Search for chemical match using the InChIKey DPYMFVXJLLWWEU-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey DPYMFVXJLLWWEU-UHFFFAOYSA-N
Wikipedia Desflurane