sotalol   Click here for help

GtoPdb Ligand ID: 7297

Synonyms: Betapace® | MJ-1999
Approved drug
sotalol is an approved drug (FDA (1992))
Compound class: Synthetic organic
Comment: Sotalol is a β-blocker & potassium channel blocker.
Marketed formulations may contain sotalol hydrochloride (PubChem CID 66245).
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: sotalol

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 86.81
Molecular weight 272.12
XLogP 1.05
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES CC(NCC(c1ccc(cc1)NS(=O)(=O)C)O)C
Isomeric SMILES CC(NCC(c1ccc(cc1)NS(=O)(=O)C)O)C
InChI InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
2350 sotalol
Synonyms Click here for help
Betapace® | MJ-1999
Database Links Click here for help
Specialist databases
GPCRdb Ligand sotalol
Reactome Drug Reactome logo R-ALL-9610985
Reactome Reaction Reactome logo R-HSA-9609310
Other databases
CAS Registry No. 3930-20-9
DrugBank Ligand DB00489
DrugCentral Ligand 2464
GtoPdb PubChem SID 178103870
PubChem CID 5253
Search Google for chemical match using the InChIKey ZBMZVLHSJCTVON-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZBMZVLHSJCTVON
Search PubMed clinical trials sotalol
Search PubMed titles sotalol
Search PubMed titles/abstracts sotalol
UniChem Compound Search for chemical match using the InChIKey ZBMZVLHSJCTVON-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey ZBMZVLHSJCTVON-UHFFFAOYSA-N
Wikipedia sotalol