sotalol   

GtoPdb Ligand ID: 7297

Synonyms: Betapace® | MJ-1999
sotalol is an approved drug (FDA (1992))
Compound class: Synthetic organic
Comment: Sotalol is a β-blocker & potassium channel blocker.
Marketed formulations may contain sotalol hydrochloride (PubChem CID 66245).
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2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 86.81
Molecular weight 272.12
XLogP 1.05
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES CC(NCC(c1ccc(cc1)NS(=O)(=O)C)O)C
Isomeric SMILES CC(NCC(c1ccc(cc1)NS(=O)(=O)C)O)C
InChI InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
InChI Key ZBMZVLHSJCTVON-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
IUPAC Name
N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide
International Nonproprietary Names
INN number INN
2350 sotalol
Synonyms
Betapace® | MJ-1999
Database Links
CAS Registry No. 3930-20-9
ChEMBL Ligand CHEMBL471
DrugBank Ligand DB00489
DrugCentral Ligand 2464
GtoPdb PubChem SID 178103870
PubChem CID 5253
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