[3H]bag-2 [Ligand Id: 8506] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1084942
  • BB3 receptor/Bombesin receptor subtype-3 in Human [ChEMBL: CHEMBL4080] [GtoPdb: 40] [UniProtKB: P32247]
  • BB3 receptor/Bombesin receptor subtype-3 in Mouse [ChEMBL: CHEMBL1075140] [GtoPdb: 40] [UniProtKB: O54798]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BB3 receptor/Bombesin receptor subtype-3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4080] [GtoPdb: 40] [UniProtKB: P32247]
ChEMBL Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay F 6.88 pEC50 133 nM EC50 Bioorg Med Chem Lett (2010) 20: 1913-1917 [PMID:20167483]
BB3 receptor/Bombesin receptor subtype-3 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075140] [GtoPdb: 40] [UniProtKB: O54798]
GtoPdb - - 8.59 pKd 2.6 nM Kd Cell Metab (2010) 11: 101-12 [PMID:20096642]
ChEMBL Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay F 8.1 pEC50 7.9 nM EC50 Bioorg Med Chem Lett (2010) 20: 1913-1917 [PMID:20167483]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]