[3H]bag-2 [Ligand Id: 8506] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1084942
  • BB3 receptor/Bombesin receptor subtype-3 in Human [ChEMBL: CHEMBL4080] [GtoPdb: 40] [UniProtKB: P32247]
  • BB3 receptor/Bombesin receptor subtype-3 in Mouse [ChEMBL: CHEMBL1075140] [GtoPdb: 40] [UniProtKB: O54798]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BB3 receptor/Bombesin receptor subtype-3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4080] [GtoPdb: 40] [UniProtKB: P32247]
ChEMBL Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay F 6.88 pEC50 133 nM EC50 Bioorg. Med. Chem. Lett. (2010) 20: 1913-1917 [PMID:20167483]
BB3 receptor/Bombesin receptor subtype-3 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075140] [GtoPdb: 40] [UniProtKB: O54798]
GtoPdb - - 8.59 pKd 2.6 nM Kd Cell Metab (2010) 11: 101-12 [PMID:20096642]
ChEMBL Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay F 8.1 pEC50 7.9 nM EC50 Bioorg. Med. Chem. Lett. (2010) 20: 1913-1917 [PMID:20167483]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]