Synonyms: deuremidevir | JT001 | Mindavi® | VV-116 | X6 hydrobromide [PMID: 34584244]
VV116 is an approved drug (China NMPA (2023))
Compound class:
Synthetic organic
Comment: VV116 is an orally available, deuterated remdesivir analogue [4-5]. It is a tri-isobutyrate ester prodrug (formulated as the hydrobromide salt) that is converted to an active nucleoside triphosphate (116-NTP) that acts as a viral RNA-dependent RNA polymerase (RdRP) inhibitor. VV116 was developed for antiviral activity against SARS-CoV-2. We drew the chemical structure as represented in Xie et al. (2021) [4].
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (China NMPA (2023)) |
Synonyms |
deuremidevir | JT001 | Mindavi® | VV-116 | X6 hydrobromide [PMID: 34584244] |
Database Links | |
GtoPdb PubChem SID | 464244134 |
PubChem CID | 163358784 |
Search Google for chemical match using the InChIKey | RVSSLHFYCSUAHY-QXMJNOOVSA-N |
Search Google for chemicals with the same backbone | RVSSLHFYCSUAHY |
UniChem Compound Search for chemical match using the InChIKey | RVSSLHFYCSUAHY-QXMJNOOVSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | RVSSLHFYCSUAHY-QXMJNOOVSA-N |