andarine [Ligand Id: 7849] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL125236 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Androgen receptor/Androgen Receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1871] [GtoPdb: 628] [UniProtKB: P10275] | ||||||||
| ChEMBL | Agonist activity at androgen receptor | F | 8.4 | pKi | 4 | nM | Ki | J Med Chem (2009) 52: 3597-3617 [PMID:19432422] |
| ChEMBL | Displacement of [3H]mibolerone from Androgen receptor (unknown origin) measured by liquid scintillation counting method | B | 8.4 | pKi | 4 | nM | Ki | J Med Chem (2022) 65: 8772-8797 [PMID:35786895] |
| GtoPdb | - | - | 8.4 | pKi | 4 | nM | Ki | J Med Chem (2009) 52: 3597-617 [PMID:19432422] |
| Androgen receptor/Androgen Receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207] | ||||||||
| ChEMBL | Displacement of [3H]mibolerone from androgen receptor in intact rat ventral prostate cytosol by competitive binding assay | B | 8.4 | pKi | 3.98 | nM | Ki | US-20070123563-A1. Selective androgen receptor modulators and method of use thereof (2007) |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
