compound 1 [PMID: 33929818] [Ligand Id: 11709] activity data from GtoPdb

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  • Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum TM90C2B [GtoPdb: 3056]
  • Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum K1 [GtoPdb: 3056]
  • Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum NF54 [GtoPdb: 3056]
  • Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7]
  • Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum 7G8 [GtoPdb: 3056]
  • Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum Dd2 [GtoPdb: 3056]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum TM90C2B [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.77 pIC50 17 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum K1 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.7 pIC50 20 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum NF54 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.74 pIC50 18 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7]
GtoPdb Parasite growth inhibition assay - 8 pIC50 10 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum 7G8 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.74 pIC50 18 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum Dd2 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.62 pIC50 24 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.