JNJ-61186372

Ligand id: 10505

Name: JNJ-61186372

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
11030 amivantamab
Synonyms
JNJ-6372 | JNJ61186372
Comments
JNJ-61186372 is a bispecific monoclonal that targets EGFR and MET [1-2]. Examination of binding by surface plasmon resonance confirms that JNJ-61186372 can bind to EGFR and MET simultaneously [1]. JNJ-61186372 binding inhibits phosphorylation of both of the target receptor tyrosine kinases in vitro.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Database Links
Specialist databases
IMGT/mAb-DB 937
Other databases
GtoPdb PubChem SID 387065587
Search PubMed clinical trials amivantamab
Search PubMed titles amivantamab
Search PubMed titles/abstracts amivantamab