dexrazoxane   Click here for help

GtoPdb Ligand ID: 7330

Synonyms: ADR-529 | Cardioxane® | ICRF-187 | Savene® | Zinecard®
Approved drug
dexrazoxane is an approved drug (FDA (1995), EMA (2006))
Compound class: Synthetic organic
Comment: Dexrazoxane is an EDTA derivative with iron-chelating activity.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 105.8
Molecular weight 268.12
XLogP -1.3
No. Lipinski's rules broken 0
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Canonical SMILES OC1=NC(=O)CN(C1)CC(N1CC(=NC(=O)C1)O)C
Isomeric SMILES OC1=NC(=O)CN(C1)C[C@@H](N1CC(=NC(=O)C1)O)C
InChI InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1995), EMA (2006))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6544 dexrazoxane
Synonyms Click here for help
ADR-529 | Cardioxane® | ICRF-187 | Savene® | Zinecard®
Database Links Click here for help
CAS Registry No. 24584-09-6
ChEMBL Ligand CHEMBL1738
DrugBank Ligand DB00380
DrugCentral Ligand 839
GtoPdb PubChem SID 178103902
PubChem CID 71384
Search Google for chemical match using the InChIKey BMKDZUISNHGIBY-ZETCQYMHSA-N
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Wikipedia Dexrazoxane