EGIS-11150 [Ligand Id: 11959] activity data from GtoPdb

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  • 5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
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  • 5-HT7 receptor in Human [GtoPdb: 12] [UniProtKB: P34969]
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  • α2C-adrenoceptor in Human [GtoPdb: 27] [UniProtKB: P18825]
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  • D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
GtoPdb - - 8.51 pKi 3.1 nM Ki Neuropharmacology (2013) 64: 254-63 [PMID:22824189]
5-HT7 receptor in Human [GtoPdb: 12] [UniProtKB: P34969]
GtoPdb - - 8.05 pKi 9 nM Ki Neuropharmacology (2013) 64: 254-63 [PMID:22824189]
α2C-adrenoceptor in Human [GtoPdb: 27] [UniProtKB: P18825]
GtoPdb - - 7.89 pKi 13 nM Ki Neuropharmacology (2013) 64: 254-63 [PMID:22824189]
D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
GtoPdb - - 6.92 pKi 120 nM Ki Neuropharmacology (2013) 64: 254-63 [PMID:22824189]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.