surinabant [Ligand Id: 9233] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL189676 (Sr147778, SR-147778, Surinabant) |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554] | ||||||||
| ChEMBL | Inhibition of [3H]CP-55940 binding to human cannabinoid receptor 1 | B | 8.46 | pKi | 3.5 | nM | Ki | J Med Chem (2005) 48: 5059-5087 [PMID:16078824] |
| GtoPdb | Inhibition of [3H]CP-55940 binding to human cannabinoid receptor 1 expressed in CHO cells | - | 8.46 | pKi | 3.5 | nM | Ki | J Pharmacol Exp Ther (2004) 310: 905-14 [PMID:15131245] |
| CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972] | ||||||||
| GtoPdb | Inhbition of [3H]-CP 55,940 binding to human CB2 receptors expressed in CHO cells | - | 6.35 | pKi | 442 | nM | Ki | J Pharmacol Exp Ther (2004) 310: 905-14 [PMID:15131245] |
| ChEMBL | Inhibition of [3H]CP-55940 binding to human cannabinoid receptor 2 | B | 6.35 | pKi | 442 | nM | Ki | J Med Chem (2005) 48: 5059-5087 [PMID:16078824] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
