ChEMBL ligand: CHEMBL313006 (Dalcetrapib, JTT-705, RO-4607381, RO4607381)
cholesteryl ester transfer protein/Cholesteryl ester transfer protein in Human [ChEMBL: CHEMBL3572] [GtoPdb: 3248] [UniProtKB: P11597] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
cholesteryl ester transfer protein/Cholesteryl ester transfer protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3572] [GtoPdb: 3248] [UniProtKB: P11597]
ChEMBL	In vitro concentration required to inhibit 50% of cholesteryl ester transfer protein mediated cholesteryl ester transfer from HDL to VLDL and LDL in human plasma	B	5.22	pIC50	6000	nM	IC50	J Med Chem (2000) 43: 3566-3572 [PMID:11000011]
ChEMBL	In vitro inhibition of CETP activity was assessed by measuring the rate of [3H]- cholesteryl ester transfer from HDL to apoprotein B-containing lipoproteins in human plasma	B	5.22	pIC50	6000	nM	IC50	Bioorg Med Chem Lett (2004) 14: 2589-2591 [PMID:15109658]
ChEMBL	Inhibition of CETP in human plasma measured every 30 mins for 120 mins by fluorescence method	B	5.39	pIC50	4100	nM	IC50	J Med Chem (2017) 60: 8466-8481 [PMID:29035537]
GtoPdb	-	-	5.39	pIC50	4100	nM	IC50	J Med Chem (2017) 60: 8466-8481 [PMID:29035537]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]