prochlorperazine   

GtoPdb Ligand ID: 7279

Synonyms: Buccastem® | Compazine® | prochlorperazine edisylate | prochlorperazine maleate
prochlorperazine is an approved drug (FDA (1956))
Compound class: Synthetic organic
Comment: Prochlorperazine is a potent phenothiazine neuroleptic.
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: prochlorperazine

2D Structure
Click here for structure editor
Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 35.02
Molecular weight 373.14
XLogP 4.57
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES CN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(Cl)cc2
Isomeric SMILES CN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(Cl)cc2
InChI InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3
InChI Key WIKYUJGCLQQFNW-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1956))
IUPAC Name
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
International Nonproprietary Names
INN number INN
699 prochlorperazine
Synonyms
Buccastem® | Compazine® | prochlorperazine edisylate | prochlorperazine maleate
Database Links
CAS Registry No. 58-38-8
ChEMBL Ligand CHEMBL728
DrugBank Ligand DB00433
DrugCentral Ligand 2274
GtoPdb PubChem SID 178103853
PubChem CID 4917
RCSB PDB Ligand P77
Search Google for chemical match using the InChIKey WIKYUJGCLQQFNW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WIKYUJGCLQQFNW
Search PubMed clinical trials prochlorperazine
Search PubMed titles prochlorperazine
Search PubMed titles/abstracts prochlorperazine
Search UniChem for chemical match using the InChIKey WIKYUJGCLQQFNW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WIKYUJGCLQQFNW
Wikipedia Prochlorperazine