compound 5 [PMID: 29579323]

Ligand id: 10038

Name: compound 5 [PMID: 29579323]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 75.63
Molecular weight 339.01
XLogP 3.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid
Synonyms
CBA
Comments
Compound 5 is reported as a selective inhibitor of the calcium-activated non-selective cation channel TRPM4 [1]. It will facilitate experiments to better understand the role of TRPM4 function in human diseases, and help provide clues for clinical lead development.
Database Links
GtoPdb PubChem SID 375973226
PubChem CID 2264067
Search Google for chemical match using the InChIKey CVQCJPCMPGKEDH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone CVQCJPCMPGKEDH
Search UniChem for chemical match using the InChIKey CVQCJPCMPGKEDH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone CVQCJPCMPGKEDH

Product suppliers

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Tocris
CBA
Cat. No. 6724