ChEMBL ligand: CHEMBL1243373
Dipeptidyl-peptidase 7/Dipeptidyl peptidase II in Human [ChEMBL: CHEMBL3976] [GtoPdb: 1605] [UniProtKB: Q9UHL4] There should be some charts here, you may need to enable JavaScript!
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487] There should be some charts here, you may need to enable JavaScript!
dipeptidyl peptidase 9/Dipeptidyl peptidase IX in Human [ChEMBL: CHEMBL4793] [GtoPdb: 2357] [UniProtKB: Q86TI2] There should be some charts here, you may need to enable JavaScript!
dipeptidyl peptidase 8/Dipeptidyl peptidase VIII in Human [ChEMBL: CHEMBL4657] [GtoPdb: 2356] [UniProtKB: Q6V1X1] There should be some charts here, you may need to enable JavaScript!
fibroblast activation protein alpha/Fibroblast activation protein alpha in Human [ChEMBL: CHEMBL4683] [GtoPdb: 2365] [UniProtKB: Q12884] There should be some charts here, you may need to enable JavaScript!
prolyl endopeptidase/Prolyl endopeptidase in Human [ChEMBL: CHEMBL3202] [GtoPdb: 2395] [UniProtKB: P48147] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Dipeptidyl-peptidase 7/Dipeptidyl peptidase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3976] [GtoPdb: 1605] [UniProtKB: Q9UHL4]
ChEMBL	Inhibition of human recombinant His-tagged DPP2 expressed in insect cells	B	4	pIC50	>100000	nM	IC50	J Med Chem (2010) 53: 6572-6583 [PMID:20718420]
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487]
ChEMBL	Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay	B	4	pIC50	>100000	nM	IC50	J Med Chem (2013) 56: 3467-3477 [PMID:23594271]
ChEMBL	Inhibition of human recombinant His-tagged DPP4 expressed in insect cells	B	4.7	pIC50	>20000	nM	IC50	J Med Chem (2010) 53: 6572-6583 [PMID:20718420]
GtoPdb	-	-	4.7	pIC50	>20000	nM	IC50	J Med Chem (2010) 53: 6572-83 [PMID:20718420]
dipeptidyl peptidase 9/Dipeptidyl peptidase IX in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4793] [GtoPdb: 2357] [UniProtKB: Q86TI2]
ChEMBL	Inhibition of human recombinant His-tagged DPP9 expressed in insect cells	B	5.57	pIC50	2700	nM	IC50	J Med Chem (2010) 53: 6572-6583 [PMID:20718420]
GtoPdb	-	-	5.57	pIC50	2700	nM	IC50	J Med Chem (2010) 53: 6572-83 [PMID:20718420]
ChEMBL	Inhibition of human DPP9 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay	B	6.38	pIC50	420	nM	IC50	J Med Chem (2013) 56: 3467-3477 [PMID:23594271]
dipeptidyl peptidase 8/Dipeptidyl peptidase VIII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4657] [GtoPdb: 2356] [UniProtKB: Q6V1X1]
GtoPdb	-	-	5.43	pIC50	3700	nM	IC50	J Med Chem (2010) 53: 6572-83 [PMID:20718420]
ChEMBL	Inhibition of human recombinant His-tagged DPP8 expressed in insect cells	B	5.43	pIC50	3700	nM	IC50	J Med Chem (2010) 53: 6572-6583 [PMID:20718420]
ChEMBL	Inhibition of human DPP8 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay	B	5.92	pIC50	1200	nM	IC50	J Med Chem (2013) 56: 3467-3477 [PMID:23594271]
fibroblast activation protein alpha/Fibroblast activation protein alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4683] [GtoPdb: 2365] [UniProtKB: Q12884]
ChEMBL	Competitive inhibition of human recombinant FAP expressed in Hi5 insect cells by Lineweaver-Burke plot analysis	B	8.1	pKi	7.9	nM	Ki	J Med Chem (2010) 53: 6572-6583 [PMID:20718420]
GtoPdb	-	-	7.72	pIC50	19	nM	IC50	J Med Chem (2010) 53: 6572-83 [PMID:20718420]
ChEMBL	Inhibition of human recombinant FAP expressed in Hi5 insect cells	B	7.72	pIC50	19	nM	IC50	J Med Chem (2010) 53: 6572-6583 [PMID:20718420]
ChEMBL	Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay	B	8.64	pIC50	2.3	nM	IC50	J Med Chem (2013) 56: 3467-3477 [PMID:23594271]
prolyl endopeptidase/Prolyl endopeptidase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3202] [GtoPdb: 2395] [UniProtKB: P48147]
ChEMBL	Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay	B	8.74	pIC50	1.8	nM	IC50	J Med Chem (2013) 56: 3467-3477 [PMID:23594271]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]