abrilumab [Ligand Id: 11531] activity data from GtoPdb

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  • integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor) in Human [GtoPdb: 2443] [UniProtKB: P13612]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor) in Human [GtoPdb: 2443] [UniProtKB: P13612]
GtoPdb Binding affinity for α4β7 receptors expressed on the surface of HuT78 cells. - 11.05 pKd 0.01 nM Kd Br J Pharmacol (2013) 169: 51-68 [PMID:23425116]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.