semaglutide [Ligand Id: 9724] activity data from GtoPdb

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  • GLP-1 receptor in Human [GtoPdb: 249] [UniProtKB: P43220]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GLP-1 receptor in Human [GtoPdb: 249] [UniProtKB: P43220]
GtoPdb Membrane radioligand displacement assay (125I-GLP-1 as tracer) performed in the absence of human serum albumin. - 9.42 pIC50 0.38 nM IC50 J Med Chem (2015) 58: 7370-80 [PMID:26308095]
GtoPdb In vitro potency assessed in BHK cells expressing the human GLP-1R and a luciferase reporter system. - 11.21 pEC50 0.01 nM EC50 J Med Chem (2015) 58: 7370-80 [PMID:26308095]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.