tepotinib [Ligand Id: 8293] activity data from GtoPdb

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  • MET proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1815] [UniProtKB: P08581]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
MET proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1815] [UniProtKB: P08581]
GtoPdb Measured in a flash-plate assay using recombinant human c-Met kinase domain and a biotinylated peptide substrate. - 8.52 pIC50 3 nM IC50 Clin Cancer Res (2013) 19: 2941-51 [PMID:23553846]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.