GtoPdb Ligand ID: 7840

Synonyms: BMS-875944 | CS-9803 | KAI-9803
Comment: The synthesis of delcasertib is described in [1]. Delcasertib is a peptidic agent which is an isozyme-selective delta protein kinase C (PKCδ) inhibitor. It consists of a cargo peptide (CSFNSYELGSL) derived from the δV1-1 portion of PKCδ which acts to inhibit PKCδ translocation, conjugated to the cell-penetrating, arginine-rich peptide sequence of the HIV type 1 transactivator protein (TAT45-57 CYGRKKRRQRRR) which acts as a cellular delivery system.
Compound class Peptide or derivative
International Nonproprietary Names
INN number INN
9466 delcasertib
BMS-875944 | CS-9803 | KAI-9803
Database Links
GtoPdb PubChem SID 223366171
PubChem CID 56843747
Search PubMed clinical trials delcasertib
Search PubMed titles delcasertib
Search PubMed titles/abstracts delcasertib