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Synonyms: anti-factor D | FCFD4514S | RG7417
Compound class: Antibody
Comment: Lampalizumab is the Fab antigen binding domain of a humanized monoclonal antibody targeting complement factor D (CFD), the rate-limiting initiator of the alternative complement pathway (AP). The humanized antibody was produced based on a mouse monoclonal (MAb 166-32) [3,5].
Peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|International Nonproprietary Names|
|anti-factor D | FCFD4514S | RG7417|
|GtoPdb PubChem SID||252166506|
|Search PubMed clinical trials||lampalizumab|
|Search PubMed titles||lampalizumab|
|Search PubMed titles/abstracts||lampalizumab|