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ChEMBL ligand: CHEMBL99895 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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SST1 receptor/Somatostatin receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1917] [GtoPdb: 355] [UniProtKB: P30872] | ||||||||
ChEMBL | Binding affinity towards Somatostatin receptor type 1 (hsst1) | B | 5.62 | pKi | 2392 | nM | Ki | J Med Chem (2002) 45: 5609-5616 [PMID:12477342] |
SST2 receptor/Somatostatin receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1804] [GtoPdb: 356] [UniProtKB: P30874] | ||||||||
GtoPdb | - | - | 11 | pKi | - | - | - | Proc Natl Acad Sci USA (1998) 95: 10836-41 [PMID:9724791] |
ChEMBL | Binding affinity towards Somatostatin receptor type 2 (hsst2) | B | 11 | pKi | 0.01 | nM | Ki | J Med Chem (2002) 45: 5609-5616 [PMID:12477342] |
ChEMBL | Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing each of the cloned human SRIF receptor (sst-2) subtypes | B | 11 | pKi | 0.01 | nM | Ki | J Med Chem (2001) 44: 2990-3000 [PMID:11520208] |
SST3 receptor/Somatostatin receptor 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2028] [GtoPdb: 357] [UniProtKB: P32745] | ||||||||
ChEMBL | Binding affinity towards Somatostatin receptor type 3 (hsst3) | B | 7.51 | pKi | 31 | nM | Ki | J Med Chem (2002) 45: 5609-5616 [PMID:12477342] |
SST4 receptor/Somatostatin receptor 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1853] [GtoPdb: 358] [UniProtKB: P31391] | ||||||||
ChEMBL | Binding affinity towards Somatostatin receptor type 4 (hsst4) | B | 7.09 | pKi | 81 | nM | Ki | J Med Chem (2002) 45: 5609-5616 [PMID:12477342] |
SST5 receptor/Somatostatin receptor 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1792] [GtoPdb: 359] [UniProtKB: P35346] | ||||||||
ChEMBL | Binding affinity towards Somatostatin receptor type 5 (hsst5) | B | 6.79 | pKi | 163 | nM | Ki | J Med Chem (2002) 45: 5609-5616 [PMID:12477342] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]