mifepristone

Ligand id: 2805

Name: mifepristone

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 40.54
Molecular weight 429.27
XLogP 4.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2000))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
(8S,11R,13S,14S,17S)-11-(4-dimethylaminophenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
5752 mifepristone
Synonyms
Mifeprex® | RU-486 | RU486
Comments
An antagonist of both the glucocorticoid receptor and the progesterone receptor.
Database Links
BindingDB Ligand 18627
CAS Registry No. 84371-65-3 (source: Scifinder)
ChEBI CHEBI:50692
ChEMBL Ligand CHEMBL1276308
DrugBank Ligand DB00834
GtoPdb PubChem SID 135650608
NURSA Ligand 10.1621/ST5A19ZOKW
PubChem CID 55245
RCSB PDB Ligand 486
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Wikipedia Mifepristone

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Tocris
Mifepristone
Cat. No. 1479