ChEMBL ligand: CHEMBL1261 (Citric acid, E-330, INS-330, E330, NSC-112226, Anhydrous citric acid, Citric Acid, Citric acid hydrate, INS NO.330, NSC-30279, NSC-626579, FEMA NO. 2306, Urologic G, Citric acid, anhydrous)
3-dehydroquinate dehydratase in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) [ChEMBL: CHEMBL4680] [UniProtKB: Q48255] 3-dehydroquinate dehydratase in Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [ChEMBL: CHEMBL5276] [UniProtKB: P15474] This target only has 0 pki data point 0 1 CHEMBL1261_lig_chart_1 3-dehydroquinate dehydratase Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori)Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) There should be some charts here, you may need to enable JavaScript!
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9] This target only has 0 pki data point 0 2 CHEMBL1261_lig_chart_2 TRPP2 Human There should be some charts here, you may need to enable JavaScript!
TRPV4 in Mouse [GtoPdb: 510] [UniProtKB: Q9EPK8] This target only has 0 pki data point 0 3 CHEMBL1261_lig_chart_3 TRPV4 Mouse There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
3-dehydroquinate dehydratase in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4680] [UniProtKB: Q48255]
ChEMBL	Binding affinity for Helicobacter pylori DHQase 2	B	5.6	pKd	2500	nM	Kd	J. Med. Chem. (2006) 49: 1282-1290 [PMID:16480265]
3-dehydroquinate dehydratase in Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5276] [UniProtKB: P15474]
ChEMBL	Binding affinity for Streptomyces coelicolor DHQase 2	B	5.14	pKd	7300	nM	Kd	J. Med. Chem. (2006) 49: 1282-1290 [PMID:16480265]
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9]
GtoPdb	-	-	1.7	pEC50	-	-	-	Proc Natl Acad Sci USA (2006) 103: 12569-74 [PMID:16891422]
TRPV4 in Mouse [GtoPdb: 510] [UniProtKB: Q9EPK8]
GtoPdb	-	-	5.6	pEC50	-	-	-	J Biol Chem (2003) 278: 22664-8 [PMID:12692122]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]