ChEMBL ligand: CHEMBL1261 (Acidum citricum, Acidum citricum monohydrate, Aciletten, Anhydrous citric acid, B1650, Citrate, Citric acid, Citric Acid, Citric acid anhydrous, Citric acid, anhydrous, Citric acid,anhydrous, Citric acid bp, Citric acid hydrate, Citric acid, hydrous, Citric acid,hydrous, Citric acid monoglyceride, Citricum acidum, E-330, E330, FEMA NO. 2306, INS-330, INS NO.330, NSC-112226, NSC-30279, NSC-626579, Urologic G)
3-dehydroquinate dehydratase in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) [ChEMBL: CHEMBL4680] [UniProtKB: Q48255] 3-dehydroquinate dehydratase in Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [ChEMBL: CHEMBL5276] [UniProtKB: P15474] There should be some charts here, you may need to enable JavaScript!
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9] There should be some charts here, you may need to enable JavaScript!
TRPV4 in Mouse [GtoPdb: 510] [UniProtKB: Q9EPK8] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
3-dehydroquinate dehydratase in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4680] [UniProtKB: Q48255]
ChEMBL	Binding affinity for Helicobacter pylori DHQase 2	B	5.6	pKd	2500	nM	Kd	J Med Chem (2006) 49: 1282-1290 [PMID:16480265]
3-dehydroquinate dehydratase in Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5276] [UniProtKB: P15474]
ChEMBL	Binding affinity for Streptomyces coelicolor DHQase 2	B	5.14	pKd	7300	nM	Kd	J Med Chem (2006) 49: 1282-1290 [PMID:16480265]
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9]
GtoPdb	-	-	1.7	pEC50	-	-	-	Proc Natl Acad Sci USA (2006) 103: 12569-74 [PMID:16891422]
TRPV4 in Mouse [GtoPdb: 510] [UniProtKB: Q9EPK8]
GtoPdb	-	-	5.6	pEC50	-	-	-	J Biol Chem (2003) 278: 22664-8 [PMID:12692122]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]