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ChEMBL ligand: CHEMBL1261 (Acidum citricum, Acidum citricum monohydrate, Aciletten, Anhydrous citric acid, B1650, Citrate, Citric acid, Citric Acid, Citric acid anhydrous, Citric acid, anhydrous, Citric acid,anhydrous, Citric acid bp, Citric acid hydrate, Citric acid, hydrous, Citric acid,hydrous, Citric acid monoglyceride, Citricum acidum, E-330, E330, FEMA NO. 2306, INS-330, INS NO.330, NSC-112226, NSC-30279, NSC-626579, Urologic G) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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3-dehydroquinate dehydratase in Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4680] [UniProtKB: Q48255] | ||||||||
ChEMBL | Binding affinity for Helicobacter pylori DHQase 2 | B | 5.6 | pKd | 2500 | nM | Kd | J Med Chem (2006) 49: 1282-1290 [PMID:16480265] |
3-dehydroquinate dehydratase in Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5276] [UniProtKB: P15474] | ||||||||
ChEMBL | Binding affinity for Streptomyces coelicolor DHQase 2 | B | 5.14 | pKd | 7300 | nM | Kd | J Med Chem (2006) 49: 1282-1290 [PMID:16480265] |
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9] | ||||||||
GtoPdb | - | - | 1.7 | pEC50 | - | - | - | Proc Natl Acad Sci USA (2006) 103: 12569-74 [PMID:16891422] |
TRPV4 in Mouse [GtoPdb: 510] [UniProtKB: Q9EPK8] | ||||||||
GtoPdb | - | - | 5.6 | pEC50 | - | - | - | J Biol Chem (2003) 278: 22664-8 [PMID:12692122] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]