almotriptan [Ligand Id: 7110] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1505 (Almotriptan, LAS 31416, LAS-31416, NSC-760092) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| 5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
| GtoPdb | Affinity of almotriptan at recombinant h5-HT1B receptors expressed in HeLa cells, determined in a radioligand displacement assay using [125I]GTI as tracer. | - | 7.92 | pIC50 | 12 | nM | IC50 | Eur J Pharmacol (2000) 410: 33-41 [PMID:11134654] |
| 5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
| GtoPdb | Affinity of almotriptan at recombinant h5-HT1D receptors expressed in HeLa cells, determined in a radioligand displacement assay using [125I]GTI as tracer. | - | 7.89 | pIC50 | 13 | nM | IC50 | Eur J Pharmacol (2000) 410: 33-41 [PMID:11134654] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
