Ligand id: 8713

Name: brolucizumab

Compound class Antibody
International Nonproprietary Names
INN number INN
10053 brolucizumab
ESBA-1008 | ESBA1008 | RTH258
Brolucizumab is an investigational single-chain variable fragment (scFv) anti-VEGF antibody targeting vascular endothelial growth factor A (VEGFA). This immunobinder was derived from a humanised anti-VEGFA rabbit monoclonal [2].
Peptide sequence and secondary structural information are available from brolucizumab's IMGT/mAb-DB record.
Peptide sequence alignment analysis of patented peptide sequences using the heavy chain variable region of brolucizumab identifies a 100% match with SEQ ID NO: 164 in patent US8349322 B2 [1].
Database Links
Specialist databases
IMGT/mAb-DB 536
Other databases
GtoPdb PubChem SID 252827371
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