Ligand id: 8713

Name: brolucizumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Given the research code assigned, it is likely that brolucizumab is the derivative designated 578minmaxT84N_V89L (protein1008) in patent US8349322 B2 [1]. Data for 578min_max (protein1008) is provided in the interaction table below.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
VEGFA Hs Antibody Binding 8.8 pKd - 1
pKd 8.8 (Kd 1.59x10-9 M) [1]