ChEMBL ligand: CHEMBL439 (Coco-diazine, Diazyl, NSC-35600, Sulfadiazina, Sulfadiazine, Sulfadiazine component of lantrisul, Sulfadiazine component of neotrizine, Sulfadiazine component of sulfaloid, Sulfadiazine component of sulfonamides duplex, Sulfadiazine component of sulfose, Sulfadiazine component of terfonyl, Sulfadiazine component of triple sulfoid, Sulfadiazine (trisulfapyrimidines), Sulfadiazine (trisulfapyrimidines) component of neotrizine, Sulfadiazine (trisulfapyrimidines) component of terfonyl, Sulfolex, Trisulfapyrimidines (sulfadiazine))
aurora kinase A/Aurora kinase A in Human [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965] There should be some charts here, you may need to enable JavaScript!
dihydrofolate reductase/Dihydrofolate reductase in Human [ChEMBL: CHEMBL202] [GtoPdb: 2603] [UniProtKB: P00374] There should be some charts here, you may need to enable JavaScript!
Plasmodium falciparum [ChEMBL: CHEMBL364] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
aurora kinase A/Aurora kinase A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965]
ChEMBL	Inhibition of aurora kinase A	B	4.68	pIC50	21000	nM	IC50	J Med Chem (2008) 51: 3661-3680 [PMID:18457385]
dihydrofolate reductase/Dihydrofolate reductase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL202] [GtoPdb: 2603] [UniProtKB: P00374]
ChEMBL	Inhibition of DHFR (unknown origin)	B	6.89	pIC50	130	nM	IC50	RSC Med Chem (2022) 13: 471-496 [PMID:35685617]
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	DNDI: Malaria in Vitro, 72 hour	F	5.84	pIC50	1440	nM	IC50	Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]