lysophosphatidylserine [Ligand Id: 4064] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL582985
  • GPR34 in Human [GtoPdb: 101] [UniProtKB: Q9UPC5]
  • GPR34 in Mouse [GtoPdb: 101] [UniProtKB: Q9R1K6]
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  • GPR174 in Human [GtoPdb: 145] [UniProtKB: Q9BXC1]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GPR34 in Human [GtoPdb: 101] [UniProtKB: Q9UPC5]
GtoPdb - - 6.89 pEC50 129 nM EC50 Biochem Biophys Res Commun (2006) 341: 1078-87 [PMID:16460680];
J Biochem (2012) 151: 511-8 [PMID:22343749]
GPR34 in Mouse [GtoPdb: 101] [UniProtKB: Q9R1K6]
GtoPdb - - 7.31 pEC50 49 nM EC50 Biochem Biophys Res Commun (2006) 341: 1078-87 [PMID:16460680]
GPR174 in Human [GtoPdb: 145] [UniProtKB: Q9BXC1]
GtoPdb - - 7.1 pEC50 81 nM EC50 Nat Methods (2012) 9: 1021-9 [PMID:22983457]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]