pimecrolimus [Ligand Id: 6783] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1200686 (Elidel, Pimecrolimus, SDZ ASM 981, SDZ ASM-981, SDZ-ASM 981, SDZ-ASM-981)
  • FKBP prolyl isomerase 1A in Rat [GtoPdb: 2609] [UniProtKB: Q62658]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
FKBP prolyl isomerase 1A in Rat [GtoPdb: 2609] [UniProtKB: Q62658]
GtoPdb Indirect measurement of primary target inhibition via rotamase inhibition - 8.22 pIC50 6 nM IC50 Arch Dermatol Res (1998) 290: 501-7 [PMID:9808344]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]