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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|SKI 2 | SKI-II|
|The discovery of this selective sphingosine kinase inhibitor is described in , where it is called compound II.
The above article cites  for the creation of the human sphingosine kinase protein used in their kinase assay. BLAST searches using the accession numbers in this article indicate the kinase assay was performed using the SPHK1 isozyme. SKI II exhibits some selectivity toward SK2 as a kinase inhibitor (Ki for SK2 = 7.9 μM vs. SK1 = 16 μM) . It is a more powerful promoter of SK1-degradation than of SK2-degradation .
|CAS Registry No.||312636-16-1|
|GtoPdb PubChem SID||178102663|
|RCSB PDB Ligand||UUL|
|Search Google for chemical match using the InChIKey||ZFGXZJKLOFCECI-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||ZFGXZJKLOFCECI|
|Search UniChem for chemical match using the InChIKey||ZFGXZJKLOFCECI-UHFFFAOYSA-N|
|Search UniChem for chemicals with the same backbone||ZFGXZJKLOFCECI|
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Cat. No. 2097