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ChEMBL ligand: CHEMBL1084106 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Cell division control protein 42 homolog in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6088] [UniProtKB: P60953] | ||||||||
ChEMBL | Inhibition of CDc42 | B | 5.1 | pIC50 | >8000 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760] |
DM1 protein kinase/Myotonin-protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5320] [GtoPdb: 1505] [UniProtKB: Q09013] | ||||||||
ChEMBL | Inhibition of DMPK | B | 5.1 | pIC50 | >8000 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760] |
protein kinase C epsilon/Protein kinase C epsilon in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156] | ||||||||
ChEMBL | Inhibition of Prkce | B | 5.1 | pIC50 | >8000 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760] |
protein kinase N2/Protein kinase N2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513] | ||||||||
ChEMBL | Inhibition of Prkcl2 | B | 5.1 | pIC50 | >8000 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760] |
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464] | ||||||||
ChEMBL | Inhibition of ROCK1 | B | 7.41 | pIC50 | 39 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760] |
GtoPdb | - | - | 7.41 | pIC50 | 39 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-9 [PMID:20462760] |
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116] | ||||||||
GtoPdb | - | - | 7.72 | pIC50 | 19 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-9 [PMID:20462760] |
ChEMBL | Inhibition of ROCK2 | B | 7.72 | pIC50 | 19 | nM | IC50 | Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]