ChEMBL ligand: CHEMBL1084106
Cell division control protein 42 homolog in Human [ChEMBL: CHEMBL6088] [UniProtKB: P60953] There should be some charts here, you may need to enable JavaScript!
DM1 protein kinase/Myotonin-protein kinase in Human [ChEMBL: CHEMBL5320] [GtoPdb: 1505] [UniProtKB: Q09013] There should be some charts here, you may need to enable JavaScript!
protein kinase C epsilon/Protein kinase C epsilon in Human [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156] There should be some charts here, you may need to enable JavaScript!
protein kinase N2/Protein kinase N2 in Human [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Cell division control protein 42 homolog in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6088] [UniProtKB: P60953]
ChEMBL	Inhibition of CDc42	B	5.1	pIC50	>8000	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760]
DM1 protein kinase/Myotonin-protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5320] [GtoPdb: 1505] [UniProtKB: Q09013]
ChEMBL	Inhibition of DMPK	B	5.1	pIC50	>8000	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760]
protein kinase C epsilon/Protein kinase C epsilon in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156]
ChEMBL	Inhibition of Prkce	B	5.1	pIC50	>8000	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760]
protein kinase N2/Protein kinase N2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513]
ChEMBL	Inhibition of Prkcl2	B	5.1	pIC50	>8000	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760]
Rho associated coiled-coil containing protein kinase 1/Rho-associated protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3231] [GtoPdb: 1503] [UniProtKB: Q13464]
ChEMBL	Inhibition of ROCK1	B	7.41	pIC50	39	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760]
GtoPdb	-	-	7.41	pIC50	39	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-9 [PMID:20462760]
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb	-	-	7.72	pIC50	19	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-9 [PMID:20462760]
ChEMBL	Inhibition of ROCK2	B	7.72	pIC50	19	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3235-3239 [PMID:20462760]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]