[3H]A804598 [Ligand Id: 5408] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL574539 (A-804598)
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
P2X7/P2X purinoceptor 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4805] [GtoPdb: 484] [UniProtKB: Q99572]
ChEMBL Binding affinity at human P2X7 receptor B 8 pIC50 10 nM IC50 Bioorg. Med. Chem. (2009) 17: 4861-4865 [PMID:19540765]
P2X7/P2X purinoceptor 7 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5183] [GtoPdb: 484] [UniProtKB: Q9Z1M0]
ChEMBL Binding affinity at mouse P2X7 receptor B 8 pIC50 10 nM IC50 Bioorg. Med. Chem. (2009) 17: 4861-4865 [PMID:19540765]
P2X7/P2X purinoceptor 7 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2496] [GtoPdb: 484] [UniProtKB: Q64663]
ChEMBL Binding affinity at rat P2X7 receptor B 8 pIC50 10 nM IC50 Bioorg. Med. Chem. (2009) 17: 4861-4865 [PMID:19540765]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]