varoglutamstat [Ligand Id: 13397] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| glutaminyl-peptide cyclotransferase in Human [GtoPdb: 2411] [UniProtKB: Q16769] | ||||||||
| GtoPdb | Binding constant determined by SPR at pH 7.6 | - | 7.77 | pKd | 17 | nM | Kd | J Pharmacol Exp Ther (2017) 362: 119-130 [PMID:28446518] |
| GtoPdb | Enzymatic inhibition constant determined at pH 8.0 | - | 7.6 | pKi | 25 | nM | Ki | J Pharmacol Exp Ther (2017) 362: 119-130 [PMID:28446518] |
| glutaminyl-peptide cyclotransferase in Mouse [GtoPdb: 2411] [UniProtKB: Q9CYK2] | ||||||||
| GtoPdb | Enzymatic inhibition constant determined at pH 8.0 | - | 7.21 | pKi | 62 | nM | Ki | J Pharmacol Exp Ther (2017) 362: 119-130 [PMID:28446518] |
| glutaminyl-peptide cyclotransferase like in Human [GtoPdb: 3289] [UniProtKB: Q9NXS2] | ||||||||
| GtoPdb | - | - | 6.01 | pIC50 | 987.7 | nM | IC50 | Signal Transduct Target Ther (2023) 8: 454 [PMID:38097557] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
