Synonyms: Taigexyn® | TG-873870 | TG873870
nemonoxacin is an approved drug (Taiwan (2014))
Compound class:
Synthetic organic
Comment: Nemonoxacin is a non-fluorinated quinolone antibacterial with broad-spectrum activity against Gram-positive and Gram-negative bacteria and atypical pathogens, including methicillin-resistant S. aureus (MRSA) and vancomycin-resistant pathogens [1-2]. It selectively inhibits bacterial DNA topoisomerase (DNA gyrase) activity.
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (Taiwan (2014)) |
IUPAC Name |
7-[(3S,5S)-3-amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4-oxoquinoline-3-carboxylic acid |
International Nonproprietary Names | |
INN number | INN |
8789 | nemonoxacin |
Synonyms |
Taigexyn® | TG-873870 | TG873870 |
Database Links | |
Specialist databases | |
Antibiotic DB | Nemonoxacin, TG-873870 (Taigexyn) |
Other databases | |
CAS Registry No. | 378746-64-6 (source: WHO INN record) |
ChEMBL Ligand | CHEMBL1213456 |
DrugBank Ligand | DB06600 |
DrugCentral Ligand | 5079 |
GtoPdb PubChem SID | 405560277 |
PubChem CID | 11993740 |
Search Google for chemical match using the InChIKey | AVPQPGFLVZTJOR-RYUDHWBXSA-N |
Search Google for chemicals with the same backbone | AVPQPGFLVZTJOR |
Search PubMed clinical trials | nemonoxacin |
Search PubMed titles | nemonoxacin |
Search PubMed titles/abstracts | nemonoxacin |
UniChem Compound Search for chemical match using the InChIKey | AVPQPGFLVZTJOR-RYUDHWBXSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | AVPQPGFLVZTJOR-RYUDHWBXSA-N |