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insulin-like growth factor 1   Click here for help

GtoPdb Ligand ID: 4971

Abbreviated name: IGF-1
Synonyms: CEP-151 | mechano growth factor (MGF) | myotrophin
Approved drug
insulin-like growth factor 1 is an approved drug (FDA (2005))
Compound class: Endogenous peptide in human, mouse or rat
Comment: The recombinant form of human IGF-1 is an approved drug, mecasermin.
Species: Human
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View more information in the IUPHAR Pharmacology Education Project: insulin-like growth factor 1

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Approved drug? Yes. US FDA (2005)
International Nonproprietary Names Click here for help
INN number INN
6372 mecasermin
Synonyms Click here for help
CEP-151 | mechano growth factor (MGF) | myotrophin
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IGF1 insulin like growth factor 1 Human prepro-insulin-like growth factor I IGF1A, insulin-like growth factor 1 (somatomedin C)
Database Links Click here for help
CATH/Gene3D 1.10.100.10
ChEMBL Ligand CHEMBL1201716
DrugBank Ligand DB01277
Ensembl Gene ENSG00000017427 (Hs)
GtoPdb PubChem SID 178101669
Human Protein Atlas ENSG00000017427 (Hs)
Search PubMed clinical trials mecasermin
Search PubMed titles mecasermin
Search PubMed titles/abstracts mecasermin
UniProtKB P05019 (Hs)
Wikipedia Mecasermin, IGF1