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Synonyms: 7F3com-2H2 | MEDI-528 | MEDI528
Compound class: Antibody
Comment: Enokizumab is a humanized monoclonal antibody targeting interleukin 9 (IL-9), being investigated for its immunomodulatory potential.
Peptide sequences for this antibody are available from its IMGT/mAb-DB record.
BLAST peptide searches using the variable regions of the heavy and light chains of the antibody reveal exact matches with sequences submitted with patent US7354584 , which correspond to antibody construct 7F3com-2H2 therein..
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|International Nonproprietary Names|
|7F3com-2H2 | MEDI-528 | MEDI528|
|GtoPdb PubChem SID||310264715|
|Search PubMed clinical trials||enokizumab|
|Search PubMed titles||enokizumab|
|Search PubMed titles/abstracts||enokizumab|