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ChEMBL ligand: CHEMBL140020 (BW-28C51) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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acetylcholinesterase (Yt blood group)/Acetylcholinesterase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL220] [GtoPdb: 2465] [UniProtKB: P22303] | ||||||||
GtoPdb | - | - | 7.7 | pIC50 | - | - | - | Neurochem Res (2003) 28: 515-22 [PMID:12675140] |
ChEMBL | Inhibitory activity against Acetylcholinesterase | B | 8.1 | pIC50 | 8 | nM | IC50 | J Med Chem (1996) 39: 5064-5071 [PMID:8978837] |
ChEMBL | Inhibition acetylcholinesterase (AChE) enzyme. | B | 8.1 | pIC50 | 8 | nM | IC50 | J Med Chem (1997) 40: 4360-4371 [PMID:9435905] |
Acetylcholinesterase in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4768] [UniProtKB: P23795] | ||||||||
ChEMBL | Inhibition of bovine AChE by Ellman's method | B | 8.1 | pIC50 | 8 | nM | IC50 | Bioorg Med Chem (2008) 16: 7450-7456 [PMID:18585045] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]