enoxaparin

Ligand id: 6811

Name: enoxaparin

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 39
Hydrogen bond donors 15
Rotatable bonds 22
Topological polar surface area 652.39
Molecular weight 1134.01
XLogP -13.27
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993), FDA (2016))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-3-[5-(6-carboxy-4,5-dihydroxy-3-sulfooxyoxan-2-yl)oxy-6-(hydroxymethyl)-3-(sulfoamino)-4-sulfooxyoxan-2-yl]oxy-4-hydroxy-5-sulfooxyoxane-2-carboxylic acid
International Nonproprietary Names
INN number INN
5452 enoxaparin sodium
Synonyms
Clexane® | enoxaparin sodium | Lovenox® | PK-10169 | RP-54563
Comments
A Low-Molecular-Weight Heparin antithrombin-III activator. It consists of fractionated material from pig mucosa but the PubChem structure represents the major form.

Biosimilar drugs: The EMA approved enoxaparin biosimilars named Inhixa and Thorinane in 2016.
Database Links
CAS Registry No. 679809-58-6
ChEMBL Ligand CHEMBL1201476
DrugBank Ligand DB01225
GtoPdb PubChem SID 178103417
Immunopaedia Search enoxaparin
PubChem CID 772
Search Google for chemical match using the InChIKey HTTJABKRGRZYRN-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey HTTJABKRGRZYRN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HTTJABKRGRZYRN
Wikipedia Enoxaparin