ChEMBL ligand: CHEMBL283807
Histidine triad nucleotide-binding protein 1 in Human [ChEMBL: CHEMBL5878] [UniProtKB: P49773] There should be some charts here, you may need to enable JavaScript!
Hypoxanthine-guanine phosphoribosyltransferase in Human [ChEMBL: CHEMBL2360] [UniProtKB: P00492] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Histidine triad nucleotide-binding protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5878] [UniProtKB: P49773]
ChEMBL	Binding affinity to full-length human N-terminal His6-tagged Hint1 expressed in Escherichia coli Rosetta 2 pLysS cells by isothermal titration calorimetry	B	4.17	pKd	67000	nM	Kd	US-20180065965-A1. SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 (null)
Hypoxanthine-guanine phosphoribosyltransferase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2360] [UniProtKB: P00492]
ChEMBL	Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assay	B	5.24	pKi	5800	nM	Ki	J Med Chem (2009) 52: 4391-4399 [PMID:19527031]
ChEMBL	Inhibition of human HGPRT	B	5.24	pKi	5800	nM	Ki	J Med Chem (2015) 58: 4822-4838 [PMID:25915781]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]