etalocib [Ligand Id: 2948] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL329123 (Etalocib, Ly-293111, Ly293111, VML 295, LY-293111, LY293111, LY-193111)
  • BLT1 receptor/Leukotriene B4 receptor 1 in Human [ChEMBL: CHEMBL3911] [GtoPdb: 267] [UniProtKB: Q15722]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BLT1 receptor/Leukotriene B4 receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3911] [GtoPdb: 267] [UniProtKB: Q15722]
ChEMBL Compound was tested for inhibitory activity against human neutrophil LTB4 receptor binding B 7.6 pKi 25 nM Ki J. Med. Chem. (1996) 39: 2629-2654 [PMID:8709092]
GtoPdb - - 7.75 pKi 17.6 nM Ki J Pharmacol Exp Ther (1999) 288: 286-94 [PMID:9862783]
GtoPdb - - 9.3 pIC50 0.5 nM IC50 J Pharmacol Exp Ther (1999) 288: 286-94 [PMID:9862783]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]