etalocib [Ligand Id: 2948] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL329123 (Etalocib, LY-193111, Ly-293111, Ly293111, LY-293111, LY293111, VML 295)
  • BLT1 receptor/Leukotriene B4 receptor 1 in Human [ChEMBL: CHEMBL3911] [GtoPdb: 267] [UniProtKB: Q15722]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BLT1 receptor/Leukotriene B4 receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3911] [GtoPdb: 267] [UniProtKB: Q15722]
ChEMBL Compound was tested for inhibitory activity against human neutrophil LTB4 receptor binding B 7.6 pKi 25 nM Ki J Med Chem (1996) 39: 2629-2654 [PMID:8709092]
GtoPdb - - 7.75 pKi 17.6 nM Ki J Pharmacol Exp Ther (1999) 288: 286-94 [PMID:9862783]
GtoPdb - - 9.3 pIC50 0.5 nM IC50 J Pharmacol Exp Ther (1999) 288: 286-94 [PMID:9862783]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]