compound 28xvii [PMID: 8809154] [Ligand Id: 8764] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL331755
  • sPLA2-1B/Phospholipase A2 group 1B in Human [ChEMBL: CHEMBL4426] [GtoPdb: 1416] [UniProtKB: P04054]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
sPLA2-1B/Phospholipase A2 group 1B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4426] [GtoPdb: 1416] [UniProtKB: P04054]
ChEMBL Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay. B 8.22 pIC50 6 nM IC50 J. Med. Chem. (1996) 39: 3636-3658 [PMID:8809154]
ChEMBL Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC). B 8.89 pIC50 1.3 nM IC50 J. Med. Chem. (1996) 39: 3636-3658 [PMID:8809154]
GtoPdb Measured using a chromogenic assay. - 8.89 pIC50 1.3 nM IC50 J Med Chem (1996) 39: 3636-58 [PMID:8809154]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]