trandolapril [Ligand Id: 6453] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1519 (Indolapril, Trandolapril, Odrik, Gopten, RU-44570, RU 44570, Mavik)
  • Angiotensin-converting enzyme in Human [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821]
  • This target only has 0 pki data point
  • 0
1 CHEMBL1519_lig_chart_1 Angiotensin-converting enzyme Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Angiotensin-converting enzyme in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821]
GtoPdb - - 7.8 pIC50 15 nM IC50 J Cardiovasc Pharmacol (1994) 23 Suppl 4: S11-5 [PMID:7527095]
ChEMBL Inhibitory activity against angiotensin I converting enzyme (ACE) B 9.03 pIC50 0.93 nM IC50 J. Med. Chem. (2000) 43: 305-341 [PMID:10669559]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]