trandolapril [Ligand Id: 6453] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1519 (Gopten, Indolapril, Mavik, NSC-758939, Odrik, RU 44570, RU-44570, Trandolapril)
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Angiotensin-converting enzyme in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821]
GtoPdb - - 7.8 pIC50 15 nM IC50 J Cardiovasc Pharmacol (1994) 23 Suppl 4: S11-5 [PMID:7527095]
ChEMBL Inhibitory activity against angiotensin I converting enzyme (ACE) B 9.03 pIC50 0.93 nM IC50 J Med Chem (2000) 43: 305-341 [PMID:10669559]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]