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ChEMBL ligand: CHEMBL1519 (Gopten, Indolapril, Mavik, NSC-758939, Odrik, RU 44570, RU-44570, Trandolapril) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Angiotensin-converting enzyme in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821] | ||||||||
GtoPdb | - | - | 7.8 | pIC50 | 15 | nM | IC50 | J Cardiovasc Pharmacol (1994) 23 Suppl 4: S11-5 [PMID:7527095] |
ChEMBL | Inhibitory activity against angiotensin I converting enzyme (ACE) | B | 9.03 | pIC50 | 0.93 | nM | IC50 | J. Med. Chem. (2000) 43: 305-341 [PMID:10669559] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]