Ligand id: 4790
Name: paroxetine
View more information in the IUPHAR Pharmacology Education Project: paroxetine
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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1992)) |
IUPAC Name ![]() |
(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine |
International Nonproprietary Names ![]() |
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INN number | INN |
4327 | paroxetine |
Synonyms ![]() |
paroxetine hydrochloride (anhydrous or hemihydrate) | Paxil® | Seroxat® |
Comments |
Paroxetine is a selective serotonin-reuptake inhibitor (SSRI) antidepressant. An X-ray structure of crystals of paroxetine bound SERT, shows a single central binding site [1] (see PDB entry 5I6X).. |
Database Links ![]() |
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CAS Registry No. | 61869-08-7 (source: Scifinder) |
ChEBI | CHEBI:7936 |
ChEMBL Ligand | CHEMBL490 |
DrugBank Ligand | DB00715 |
GtoPdb PubChem SID | 178101492 |
PubChem CID | 43815 |
RCSB PDB Ligand | 8PR |
Search Google for chemical match using the InChIKey | AHOUBRCZNHFOSL-YOEHRIQHSA-N |
Search Google for chemicals with the same backbone | AHOUBRCZNHFOSL |
Search PubMed clinical trials | paroxetine |
Search PubMed titles | paroxetine |
Search PubMed titles/abstracts | paroxetine |
Search UniChem for chemical match using the InChIKey | AHOUBRCZNHFOSL-YOEHRIQHSA-N |
Search UniChem for chemicals with the same backbone | AHOUBRCZNHFOSL |
SynPHARM |
13002 (in complex with SERT) 83552 (in complex with SERT) |
Wikipedia | Paroxetine |