Classification
Compound class	Synthetic organic
Approved drug?	Yes (FDA (1992))

IUPAC Name

(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine

International Nonproprietary Names
INN number	INN
4327	paroxetine

Synonyms

paroxetine hydrochloride (anhydrous or hemihydrate) | Paxil® | Seroxat®

Comments

Paroxetine is a selective serotonin-reuptake inhibitor (SSRI) antidepressant. An X-ray structure of crystals of paroxetine bound SERT, shows a single central binding site [1] (see PDB entry 5I6X)..

Database Links
CAS Registry No.	61869-08-7 (source: Scifinder)
ChEBI	CHEBI:7936
ChEMBL Ligand	CHEMBL490
DrugBank Ligand	DB00715
GtoPdb PubChem SID	178101492
PubChem CID	43815
RCSB PDB Ligand	8PR
Search Google for chemical match using the InChIKey	AHOUBRCZNHFOSL-YOEHRIQHSA-N
Search Google for chemicals with the same backbone	AHOUBRCZNHFOSL
Search PubMed clinical trials	paroxetine
Search PubMed titles	paroxetine
Search PubMed titles/abstracts	paroxetine
Search UniChem for chemical match using the InChIKey	AHOUBRCZNHFOSL-YOEHRIQHSA-N
Search UniChem for chemicals with the same backbone	AHOUBRCZNHFOSL
SynPHARM	13002 (in complex with SERT) 83552 (in complex with SERT)
Wikipedia	Paroxetine