Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL225111 (Lanostereol) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
Alpha-crystallin B chain in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3621022] [UniProtKB: P02511] | ||||||||
ChEMBL | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | B | 5.85 | pEC50 | 1420 | nM | EC50 | J Med Chem (2018) 61: 8693-8706 [PMID:30153006] |
Farnesoid X receptor-β in Mouse [GtoPdb: 604] | ||||||||
GtoPdb | - | - | 6 | pEC50 | - | - | - | Mol Cell Biol (2003) 23: 864-72 [PMID:12529392] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]