4-(n-propyl)amino-3-nitrobenzoic acid [Ligand Id: 5801] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL236011
  • HCA3 receptor/HM74 nicotinic acid GPCR in Human [ChEMBL: CHEMBL4421] [GtoPdb: 313] [UniProtKB: P49019]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
HCA3 receptor/HM74 nicotinic acid GPCR in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4421] [GtoPdb: 313] [UniProtKB: P49019]
GtoPdb - - 7.52 pEC50 30 nM EC50 Bioorg Med Chem Lett (2007) 17: 6619-22 [PMID:17931863]
ChEMBL Agonist activity at human GPR109b receptor transfected in CHOK1 cells assessed as reversal of forskolin-induced cAMP elevating effect by whole cell assay F 7.53 pEC50 29.51 nM EC50 Bioorg. Med. Chem. Lett. (2007) 17: 6619-6622 [PMID:17931863]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]