decyl dihydrogen phosphate [Ligand Id: 4030] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL361255 (Phosphoric Acid Monodecyl Ester)
  • LPA2 receptor/Lysophosphatidic acid receptor Edg-4 in Human [ChEMBL: CHEMBL3724] [GtoPdb: 273] [UniProtKB: Q9HBW0]
  • This target only has 0 pki data point
1 CHEMBL361255_lig_chart_1 Lysophosphatidic acid receptor Edg-4 Human
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  • LPA3 receptor/Lysophosphatidic acid receptor Edg-7 in Human [ChEMBL: CHEMBL3250] [GtoPdb: 274] [UniProtKB: Q9UBY5]
  • This target only has 1 pki data point
2 CHEMBL361255_lig_chart_2 Lysophosphatidic acid receptor Edg-7 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
LPA2 receptor/Lysophosphatidic acid receptor Edg-4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3724] [GtoPdb: 273] [UniProtKB: Q9HBW0]
GtoPdb - - 5.4 pEC50 3700 nM EC50 Mol. Pharmacol. (2003) 63: 1032-42 [PMID:12695531]
ChEMBL Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA2 receptor F 5.74 pEC50 1800 nM EC50 J. Med. Chem. (2005) 48: 4919-4930 [PMID:16033271]
LPA3 receptor/Lysophosphatidic acid receptor Edg-7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3250] [GtoPdb: 274] [UniProtKB: Q9UBY5]
ChEMBL Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells B 6.92 pKi 121 nM Ki J. Med. Chem. (2005) 48: 4919-4930 [PMID:16033271]
ChEMBL Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor F 6.42 pIC50 384 nM IC50 J. Med. Chem. (2005) 48: 4919-4930 [PMID:16033271]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]