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ChEMBL ligand: CHEMBL361255 (Phosphoric Acid Monodecyl Ester) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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LPA2 receptor/Lysophosphatidic acid receptor Edg-4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3724] [GtoPdb: 273] [UniProtKB: Q9HBW0] | ||||||||
GtoPdb | - | - | 5.4 | pEC50 | 3700 | nM | EC50 | Mol Pharmacol (2003) 63: 1032-42 [PMID:12695531] |
ChEMBL | Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA2 receptor | F | 5.74 | pEC50 | 1800 | nM | EC50 | J. Med. Chem. (2005) 48: 4919-4930 [PMID:16033271] |
LPA3 receptor/Lysophosphatidic acid receptor Edg-7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3250] [GtoPdb: 274] [UniProtKB: Q9UBY5] | ||||||||
ChEMBL | Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells | B | 6.92 | pKi | 121 | nM | Ki | J. Med. Chem. (2005) 48: 4919-4930 [PMID:16033271] |
ChEMBL | Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | F | 6.42 | pIC50 | 384 | nM | IC50 | J. Med. Chem. (2005) 48: 4919-4930 [PMID:16033271] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]