vepugratinib [Ligand Id: 14366] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362] | ||||||||
| GtoPdb | - | - | 6.76 | pIC50 | 174.5 | nM | IC50 | Mol Cancer Ther (2021) 20: P141 |
| fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802] | ||||||||
| GtoPdb | - | - | 7.04 | pIC50 | 90.7 | nM | IC50 | Mol Cancer Ther (2021) 20: P141 |
| fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607] | ||||||||
| GtoPdb | FGFR3 S249C/V555M | - | 8.3 | pIC50 | 5 | nM | IC50 | Mol Cancer Ther (2021) 20: P141 |
| GtoPdb | FGFR3 S249C | - | 8.51 | pIC50 | 3.1 | nM | IC50 | Mol Cancer Ther (2021) 20: P141 |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
