AS-1517499 [Ligand Id: 14435] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL228192 (AS-1517499) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| signal transducer and activator of transcription 6/Signal transducer and activator of transcription 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5401] [GtoPdb: 2993] [UniProtKB: P42226] | ||||||||
| ChEMBL | Inhibition of STAT6 in human IL4-stimulated FW4 cells | B | 7.68 | pIC50 | 21 | nM | IC50 | Bioorg Med Chem (2007) 15: 1044-1055 [PMID:17071093] |
| ChEMBL | Inhibition of STAT6 activation in FW4 reporter cells | B | 7.68 | pIC50 | 21 | nM | IC50 | Bioorg Med Chem (2008) 16: 6509-6521 [PMID:18534856] |
| GtoPdb | - | - | 7.68 | pIC50 | 21 | nM | IC50 | Bioorg Med Chem (2007) 15: 1044-55 [PMID:17071093] |
ChEMBL data shown on this page come from version 37:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
